The Correlation between Bone Mineral Density and Particulate Matter in Patients with Osteoporosis

Seyed Mohammad  Mohammadi; Mohammad  Lotfi; Naser  Kamyari; Fatemeh Shojaei  Moghaddam; Gholamreza  Goudarzi; Heydar  Maleki; Jasem  Salehi; Seyed Amin Hossaini  Motlagh; Khadijeh                                                                                                                                                                                                                                                        Kanani; Sheyda  Ghasemi; Esmat  Radmanesh

doi:10.18502/jost.v12i2.21512

Seyed Mohammad Mohammadi Assistant Professor, Department of Orthopedics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Mohammad Lotfi Medical Student, Student Research Committee, Abadan University of Medical Sciences, Abadan, Iran
Naser Kamyari Assistant Professor, Department of Public Health, School of Health, Abadan University of Medical Sciences, Abadan, Iran
Fatemeh Shojaei Moghaddam Medical Student, Student Research Committee, Abadan University of Medical Sciences, Abadan, Iran
Gholamreza Goudarzi Professor, Air Pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Heydar Maleki PhD Candidate, Air Pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Jasem Salehi Clinical Research Development Unit, Taleghani Educational Hospital, Abadan University of Medical Sciences, Abadan, Iran
Seyed Amin Hossaini Motlagh Associate Professor, Department of Environmental Health Engineering, School of Health, Yasuj University of Medical Sciences, Yasuj, Iran
Khadijeh Kanani Clinical Research Development Unit, Taleghani Educational Hospital, Abadan University of Medical Sciences, Abadan, Iran
Sheyda Ghasemi Medical Student, Student Research Committee, Abadan University of Medical Sciences, Abadan, Iran
Esmat Radmanesh Associate Professor, Research Center for Environmental Contaminants (RCEC), Abadan University of Medical Sciences, Abadan, Iran

DOI: https://doi.org/10.18502/jost.v12i2.21512

Keywords: Osteoporosis; Femur; Particulate Matter

Abstract

Background: This study examined the correlation between bone mineral density (BMD) and particulate matter (PM) in patients with osteoporosis.

Methods: People with osteopenia, osteoporosis, and normal BMD were included in the study. BMD, bone mineral content (BMC), T-scores, and Z-scores of the lumbar vertebrae (L1-L4) and femur were obtained by dual-energy X-ray absorptiometry (DEXA). Daily PM2.5 and PM10 concentrations during the study period (January 21, 2022, to May 21, 2023) were obtained from local monitoring stations, with missing data estimated using satellite-derived aerosol optical depth (AOD).

Results: In patients with osteoporosis, inverse correlations were observed between PM2.5 and PM10 and BMD, BMC, T-scores, and Z- scores in different parts of the femur (except femoral neck T-score) and lumbar spine. Still, none of the correlations was statistically significant.

Conclusion: There was no significant correlation between the mean concentration of PM2.5 and PM10 and the parameters of BMD, BMC, T-score, and Z-score in the bones of the femur and lumbar spine of patients with osteoporosis.