Thermal Simulation and Detection of Breast Tumor Using Passive Acoustic Thermometry

Hossein  Amiri; Ali  Khani; Seyed Hani  Hozhabr; Yousef  Moghimi Boldaji; Bahador  Makki Abadi

doi:10.18502/fbt.v9i2.8847

Hossein Amiri Department of Medical Physics and Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Ali Khani School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran
Seyed Hani Hozhabr Research Center for Biomedical Technologies and Robotics, Tehran University of Medical Sciences, Tehran, Iran
Yousef Moghimi Boldaji Department of Medical Physics, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Bahador Makki Abadi Department of Medical Physics and Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

DOI: https://doi.org/10.18502/fbt.v9i2.8847

Keywords: Internal Temperature; Passive Acoustic Thermometer; Breast Tumor Simulation.

Abstract

Purpose: For over three decades, various researchers have aimed to construct a model of breast cancer. Most of them have used an infrared thermal model to stimulate breast cancer, but in this study, a novel estimation methodology is presented to detect the breast cancer tumor using the surface measurement obtained by Passive Acoustic Thermometer (PAT). PAT is a safe method for internal temperature estimation that works based on acoustic radiation of materials with a specific temperature.

Materials and Methods: This article uses a simulation framework for breast tissue simulation and tumor detection using the PAT methodologies in different scenarios. This framework supports the generation of acoustic radiation, tissue modelling, signal processing, parameter estimation, and temperature reconstruction processes. The proposed framework estimates the temperature in the frequency domain and uses the frequency spectrum of the acquired ultrasound signals captured by a single transducer. Using the proposed framework, PAT has been evaluated in breast cancer detection.

Results: According to the results, obtained from the temperature estimation in scenario 3, the sub-band estimation method, which is utilized in practical experiments in this field, shows different errors in each sub-band, making it difficult to select the true estimation. Therefore, a novel formulation is proposed that provides only one estimated temperature for breast tissue with a reasonable error (1.28 degrees) for tumor detection.

Conclusion: The results show that it is possible to use this framework to evaluate the PAT in different scenarios for tumor detection. In fact, this method enhances the possibility of examination of different conditions and algorithms. It also reduces the cost of practical experiments.