Clinical Usage of Tissue Electrical Conductivity during the Electroporation: An Essential and Useful Factor

Abstract

Electric field intensity at each point is responsible for pore creation in the cell membrane during the electroporation process. These pores can increase the tissue electrical conductivity in the electroporation. Changes in electrical conductivity through the electroporation is a useful factor for imaging and tracking of electroporation inside the body. Electrical conductivity is set to become a vital factor for accurate estimation of the electric field and cell kill probability distribution in the course of electroporation for treatment planning purposes. Therefore, for more accurate treatment, tissue electrical conductivity changes due to electroporation should be considered in the treatment planning system. This paper describes the advantages of tissue electrical conductivity as a useful factor in the clinic.