The Diagnostic Value of Multiparametric-MRI in Locating Prostate Cancer in Comparison with Transrectal Ultrasound-Guided Biopsy

Sayed Mohammad  Sakhaei; Sedighe Rahmani  Firouzi; Mohamad Ghazanfari  Hashemi; Seyedeh Nooshin  Miratashi Yazdi; Mohammad Ali  Kaviani; Maryam  Alaei; Helia  Helali; Maedeh Ghazanfari  Hashemi; Marjan  Gholami; Vahid  Talebi

doi:10.18502/fbt.v11i2.15334

Sayed Mohammad Sakhaei Department of Radiology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Sedighe Rahmani Firouzi Department of Radiology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Mohamad Ghazanfari Hashemi Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran
Seyedeh Nooshin Miratashi Yazdi Advanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, Iran
Mohammad Ali Kaviani Department of Radiology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
Maryam Alaei School of Medicine, Shahid Beheshti Medical University, Tehran, Iran
Helia Helali School of Medicine, Shahid Beheshti Medical University, Tehran, Iran
Maedeh Ghazanfari Hashemi School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran
Marjan Gholami School of Pharmacy, Islamic Azad University Pharmaceutical Sciences Branch, Tehran, Iran
Vahid Talebi Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran

DOI: https://doi.org/10.18502/fbt.v11i2.15334

Keywords: Prostate Cancer; Magnetic Resonance Imaging; Ultrasound; Biopsy.

Abstract

Purpose: The present study was designed to evaluate the potential efficacy of Multiparametric-Magnetic Resonance Imaging (MP-MRI) in the detection of prostate cancer locations compared to Transrectal Ultrasound (TRUS) guided biopsy, as the gold standard method.

Materials and Methods: A total of 66 subjects participated in this cross-sectional study. All individuals underwent MP-MRI imaging before the prostate TRUS. The findings of either method have been investigated and the comparison had been made using the Chi-squared test.

Results: The sensitivity and specificity of the MP-MRI in the diagnosis of prostate cancer were 81.8% and 93.9%, respectively. The positive and negative predictive values were 93.1% and 83.8%, respectively.

Conclusion: The current study indicates that the MP-MRI imaging method has sufficient sensitivity and specificity for detecting the location of prostate cancer and can potentially be employed as a clue-providing method prior to the TRUS-guided biopsy.