Intracardiac Thrombosis in A Neonate: A Case Report

Seyed Reza Mirjalili; Morteza Danaeian; Fatemeh Baghalsafa

doi:10.18502/wjpn.v4i1.7547

Seyed Reza Mirjalili Department of Pediatrics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Morteza Danaeian Department of Pediatrics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Fatemeh Baghalsafa Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

DOI: https://doi.org/10.18502/wjpn.v4i1.7547

Keywords: Thrombosis; Neonate; Recombinant tissue plasminogen; Rivaroxaban

Abstract

Background: Life-threatening intracardiac thrombosis is rare. Intracardiac thrombosis may affect neonates from the first months of life. Because of the potential risk of serious bleeding, the use of recombinant plasminogen activator (rt-PA) in neonates along with heparin is controversial.

Case Report: We reported a 37- day- old term infant presented with fever, restlessness, malaise, and respiratory acidosis. Right atrial thrombose was identified by ECHO, results of laboratory tests, and examination. She was successfully treated with rt-PA and rivaroxaban.

Conclusion: Early echocardiographic detection before the clot grows large and organized, allows complete, safe, and rapid thrombolysis with rt-PA and rivaroxaban.