Evaluation of Ovarian Reserve in Women with Rheumatoid Arthritis

  • Sara Patricia Peña-Lizola Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Dr. José Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico
  • Luis Humberto Sordia-Hernandez Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Dr. José Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico
  • Selene Marysol Garcia-Luna Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Dr. José Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico
  • Otto Valdes-Martinez Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Dr. José Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico
  • Cassandra Michele Skinner-Taylor Rheumatology and Immunology Service, Dr. Jose Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico
  • Mario Alberto Garza-Elizondo Rheumatology and Immunology Service, Dr. Jose Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico
  • Oscar Vidal-Gutierrez Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Dr. José Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico
  • Jesus Zacarias Villarreal-Perez Department of Endocrinology, Dr. Jose Eleuterio González University Hospital, Autonomous University of Nuevo Leon. Monterrey, Mexico
  • Miryam Eguia-Bernal Rheumatology and Immunology Service, Dr. Jose Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico
  • Felipe Arturo Morales-Martinez Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Dr. José Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico
DOI: https://doi.org/10.18502/jfrh.v15i4.7889
Keywords: Ovarian Reserve; Anti-Mullerian Hormone; Rheumatoid Arthritis

Abstract

Objective: Subfertility is commonly observed in patients with rheumatoid arthritis (RA). Although the causes are not well established, the alteration of the ovarian reserve is thought to contribute to the lower chances of pregnancy. This cross-sectional study aimed to evaluate the ovarian reserve in patients with RA.

Materials and methods: Two parameters associated with ovarian reserves such as the antral follicle count (AFC) and the anti-müllerian hormone (AMH) were assessed in 38 patients with RA. We also analyzed the correlation of these parameters with the medication used to treat this pathology and with the illness severity.

Results: The AMH levels in women with RA were comparable to those found on healthy individuals although the RA patients were more likely to have a low AFC. Ovarian reserve and RA were neither influenced by parameters of disease activity nor by the use of medication.

Conclusion: The ovarian reserve in women with RA was similar to that found in healthy individuals.

Published
2021-11-29
Issue
Volume (15) issue (4)
Section
Articles