Seroprevalence of Human Toxocariasis in Children (5–15-Year-Old) Using ELISA Method in Ardabil District, North-West of Iran

Zahra  Heidari; Zahra  Alizadeh; Hamid  Afzoun Khiyavi; Soheila  Molaei; Abdollah  Mahdavi; Behnam  Mohammadi-Ghalehbin

doi:10.18502/ijpa.v17i1.9011

Zahra Heidari Department of Medical Microbiology, Parasitology and Immunology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
Zahra Alizadeh Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Hamid Afzoun Khiyavi Health Center Laboratory, Ardabil University of Medical Sciences, Ardabil, Iran
Soheila Molaei Zoonoses Research Center, Ardabil University of Medical Sciences, Ardabil, Iran
Abdollah Mahdavi Department of Health Information Management, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
Behnam Mohammadi-Ghalehbin Department of Medical Microbiology, Parasitology and Immunology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran

DOI: https://doi.org/10.18502/ijpa.v17i1.9011

Keywords: Seroepidemiology; Human toxocariasis; Iran

Abstract

Background: Toxocariasis is a worldwide-distributed helminth parasitic infection. This study aimed to evaluate the seroprevalence of human toxocariasis in children living in Ardabil Province, North-West of Iran.

Methods: A seroepidemiological study to evaluate human toxocariasis among urban and rural populations of Ardabil County, North-West of Iran using ELISA test was carried out from 2019 to 2020. The study population was 472 children (185 females and 287 males) aged between 5 and 15 yr old. Immunoglobulin G antibodies against Toxocara spp. were analyzed by ELISA test.

Results: Of the 472 collected serum samples, 66 (14.0%) were positive for antibodies against human toxocariasis. The highest prevalence of infection was observed in children with age groups of 5-6 years. Data demonstrate higher seroprevalence among males (15.3%) than females (11.8%). Rural areas prevalence was significantly higher (24.4%) than the urban area (8.65%). The rate of the diseases was 22.8% in children having history of contact with dog.

Conclusion: Toxocariasis is prevalent in the children of Ardabil region. The present study can increase the awareness of the population about the risk of zoonotic diseases as well as the anthelmintic treatment of dogs by veterinarians and, more importantly, the control of stray dogs.