Toxoplasma gondii: A Possible Inducer of Oxidative Stress in Re-productive System of Male Rats
DOI:
https://doi.org/10.18502/ijpa.v15i4.4857Keywords:
Toxoplasmosis; Rat; Oxidative Stress; Superoxide dismutase; Catalase; MalondialdehAbstract
Results: After post inoculation, the variations of the OSMs in the testis tissue of infected rats were as follows: a significant decrease of SOD on day 80 (P=0.03), and CAT activity were detected on day 60 and 80 (P=0.04 and P=0.01) respectively. In addition, GSH (P =0.01) and TAC (P =0.03) concentration were significantly reduced on day 80. On the contrary, the concentration of MDA (P =0.01) was increased 70 days after infection. In addition, consistent changes with the tissue testis were observed in the serum OSMs of infected rats.
Conclusion: T. gondii infection caused oxidative stress in testis tissue. Thus, the adverse effects of oxidative stress may affect the male rat reproductive system.
