Seropositivity to Cysticercosis in School-Age Children Living in a Low-Income Municipality in the Midwest Region of Brazil

Dayane  Moraes; Émelin Alves  Dos Santos; José Antônio  Alves Mendes; Ivanildes Solange  Da Costa Barcelos; João Batista  Alves De Souza; Maria Do Rosário De Fátima   Gonçalves-Pires; Julia Maria  Costa-Cruz; Rosângela Maria  Rodrigues

doi:10.18502/ijpa.v18i2.13187

Dayane Moraes Parasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil
Émelin Alves Dos Santos Parasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil
José Antônio Alves Mendes Parasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil
Ivanildes Solange Da Costa Barcelos Immunology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil
João Batista Alves De Souza Parasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil
Maria Do Rosário De Fátima Gonçalves-Pires Parasitic Diagnosis Laboratory, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais State, Brazil
Julia Maria Costa-Cruz Parasitic Diagnosis Laboratory, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais State, Brazil
Rosângela Maria Rodrigues Parasitology Laboratory, Health Sciences Academic Unit, Federal University of Jataí, Goiás State, Brazil

DOI: https://doi.org/10.18502/ijpa.v18i2.13187

Keywords: Cysticercosis; Child health; Students; Seroprevalence; Brazil

Abstract

Background: Human cysticercosis (CC) is a global public health problem, especially in Latin America, including Brazil. We aimed to analyze the seroprevalence of CC among school-age children and adolescents.

Methods: We analyzed the presence of specific IgG antibodies against Taenia solium metacestodes in 500 serum samples from elementary school children and adolescents in Jataí City, state of Goiás, Brazil. IgG antibodies against the antigenic extract of the parasite were detected and analyzed by ELISA, and specific peptides were identified by confirmatory Western Blotting test.

Results: Of the 500 study participants, 205 (41%) were male, and 295 (59%) were female. Participants aged between 4 and 18 years (mean age 8.4 years). The percentage of serum samples reactive by ELISA was 37.2%. These samples were analyzed by Western Blotting, which confirmed that the seropositivity rate was 6.2% (95% CI 2.4–14.7) in 31 samples reactive for CC-specific bands, determined in serum samples from 18 male (5–11 years old) and 13 female (4–12 years old) students.

Conclusion: The CC seroprevalence demonstrated in schoolchildren suggests that this parasitosis is endemic in the study area. Further investigations are necessary to clarify the local epidemiology of this parasitosis.