A Case of Deep Venous Thrombosis in an HIV-Infected Patient despite Therapeutic Anticoagulation

Wajeeha Aiman; Muhammad  Ashar Ali; Navjot Grewal; Nyan  Bethel; Andreas A. Savopoulos; Gunwant          Guron

doi:10.18502/ijhoscr.v18i2.15379

Wajeeha Aiman Saint Michael’s Medical Center, New York College of Medicine, Newark, NJ, USA
Muhammad Ashar Ali Saint Clare’s and St. Mary’s General Hospital, Denville, NJ, USA
Navjot Grewal Saint Michael’s Medical Center, New York College of Medicine, Newark, NJ, USA
Nyan Bethel Saint Michael’s Medical Center, New York College of Medicine, Newark, NJ, USA
Andreas A. Savopoulos Saint Michael’s Medical Center, New York College of Medicine, Newark, NJ, USA
Gunwant Guron Saint Michael’s Medical Center, New York College of Medicine, Newark, NJ, USA

DOI: https://doi.org/10.18502/ijhoscr.v18i2.15379

Keywords: Deep venous thrombosis; Anti-coagulants; Human immunodeficiency virus (HIV); Enoxaparin

Abstract

Patients with human immunodeficiency virus (HIV) infection have an increased likelihood of venous thromboembolism (VTE) owing to factors such as acquired protein C and S deficiency, antiphospholipid antibody syndrome, and heightened levels of pro-inflammatory cytokines. This case report highlights an exceptionally uncommon occurrence of deep venous thrombosis in an HIV-infected patient receiving a therapeutic dose of enoxaparin. This underscores the need for cautious consideration of the risk of VTE in HIV-infected individuals, even with preventive or therapeutic anticoagulant treatment. Further research is recommended to investigate HIV as a potential risk factor of prophylactic anticoagulation.