Correlations Between Epidemiological and Clinical Characteristics, Laboratory Tests and CT Scan Reports in the Diagnosis of COVID-19: A Diagnostic Accuracy Study

Bobby Branson; Ramin Tavakoli; Mansoor Khaledi; Javad Fathi; Seyed Mohammad Shafiee; Hamed Afkhami; Shahdokht Rastegar

doi:10.18502/acta.v59i10.7761

Bobby Branson Department of Surgery, Jessenius Faculty of Medicine in Martin, Biomedical Centre Martin, Comenius University in Bratislava, Martin, Slovakia
Ramin Tavakoli Department of Biochemistry, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Mansoor Khaledi Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran
Javad Fathi Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Seyed Mohammad Shafiee Department of Biochemistry, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Hamed Afkhami Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran
Shahdokht Rastegar Toxicology Research Center, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

DOI: https://doi.org/10.18502/acta.v59i10.7761

Keywords: Clinical outcomes; Laboratory findings; Coronaviruses; Coronavirus disease 2019 (COVID-19) infections; CT scan reports

Abstract

Although the relationship between laboratory parameters, radiology, CT scan scan and clinical outcomes has not been well evaluated so far, COVID-19 is still a good challenge for this purpose. These tests can be used to diagnose, monitor, and treat COVID-19. The study was conducted from February 20 to August 31, 2020, following the referral of 340 patients with coronavirus symptoms at Chamran Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. Clinical information of each patient is obtained based on patient information forms when visiting the hospital. Comparison of the relationship between lung involvement in CT scan and laboratory indicators, including biochemical and hematological factors is a suitable and reliable comparison to identify people with Covid 19. Based on the results of this study, it was found that ALT, AST, CRP, NEU, LDH, and Urea could be a suitable diagnostic method in positive RT-PCR for COVID-19. In this study, we tried to investigate the relationship between clinical and laboratory findings with CT-based quantitative score of pulmonary involvement in COVID-19 pneumonia and as a suitable and reliable method in continuing COVID-19 pandemic and diagnosis of COVID-19 infection.