Oral Paraneoplastic Pemphigus and Pharyngeal Squamous Cell Carcinoma: A Rare Case Report and Review of Literature

Abstract

Paraneoplastic pemphigus (PNP) is an autoimmune vesiculobullous disease of the skin and mucous membrane associated with benign and malignant neoplasm. The most common malignancies associated with PNP are hematologic and lymphomatoid. Association of oral PNP with squamous cell carcinoma of the pharynx is very scarce, very few cases are reported, and also the cases of PNP are usually refractory to the treatment mainly those associated with hematologic. Here, we reported a case of oral paraneoplastic pemphigus with squamous cell carcinoma of the pharynx that resolved on its own after completion of treatment of pharyngeal squamous cell carcinoma.