Exploring the Relationship Between Migraine and Blood Pressure in Pediatric Patients: A Case-Control Study

  • Saba Rezazadeh Student Research Committee, Arak University of Medical Sciences, Arak, Iran
  • Amirabbas Faridpour Student Research Committee, Arak University of Medical Sciences, Arak, Iran
  • Fakhreddin Shariatmadari Department of Pediatric Nourology, Clinical Research Development Center of Amirkabir Hospital, Arak University of Medical Sciences, Arak, Iran
  • Yazdan Ghandi Department of Pediatric Cardiology, Clinical Research Development Center of Amirkabir Hospital, Arak University of Medical Sciences, Arak, Iran
  • Seyed Mojtaba Hashemi Departement of Pediatric Gastroenterology, Clinical Research Development Center of Amirkabir Hospital, Arak University of Medical Sciences, Arak, Iran
  • Parsa Yousefichaijan Department of Pediatric Nephrology, Clinical Research Development Center of Amirkabir Hospital, Arak University of Medical Sciences, Arak, Iran
Keywords: Blood pressure; Headache; Hypertension; Migraine; Paediatric

Abstract

Migraine headaches are a significant concern for both parents and primary care providers due to their frequency and impact on the child's quality of life. Studies in the adult population have shown that migraines are linked to cardiovascular disease. This study aimed to compare blood pressure in children with and without Migraine. In this case-control study, we evaluated blood pressure in patients with Migraine and a control group. Blood pressure was evaluated during three clinic visits. Systolic, diastolic, pulse, and mean arterial blood pressure were compared between the two groups, and the association between blood pressure and Migraine was evaluated using the odds ratio. The mean systolic and diastolic pressures, pulse pressure, and mean arterial pressure were not significantly different between the two groups (P>0.05). Twenty-three children with Migraine had abnormal blood pressure, and the adjusted odds ratio was 1.32 (95% CI: 0.68-2.57). There was no significant relationship between prehypertension, stage 1 hypertension, and stage 2 hypertension and Migraine in children (P>0.05). The prevalence of prehypertension in children with bilateral Migraine was higher compared to unilateral Migraine, although this difference was not statistically significant (P>0.05). Our results did not confirm blood pressure as an etiological factor in children with Migraine. These findings suggest that further research is needed to explore the relationship between Migraine and blood pressure in pediatric populations.

Published
2026-01-04
Section
Articles