Brain Tumor Presenting Mania Symptoms: A Case Report

Seyed Hamzeh  Hosseini; Hamed  Ghazvini; Seyedeh Masoumeh  Seyedhosseini Tamijani; Raheleh  Rafaiee

doi:10.18502/acta.v63i4.20174

Seyed Hamzeh Hosseini Department of Psychiatry, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Hamed Ghazvini Department of Neuroscience, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Seyedeh Masoumeh Seyedhosseini Tamijani Department of Neuroscience, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Raheleh Rafaiee Psychiatry and Behavioral Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran

DOI: https://doi.org/10.18502/acta.v63i4.20174

Keywords: Meningioma; Neurosurgery; Glioma; Brain tumor; Psychiatric symptom

Abstract

Brain tumors manifest with neurological symptoms as a result of mass effects. Occasionally, brain tumors may manifest with an initial psychiatric presentation in the absence of neurological deficits or symptoms. We present a case of a 54-year-old woman who showed increased energy, elevated mood, delusions, and headache. Symptoms of psychosis and mania began about two months ago and have worsened over the past month. Neurological examinations are normal. MRI of the brain confirmed the tumor on the left frontal lobe. A craniotomy and tumor resection were performed and the final diagnosis was meningioma (meningotheliomatous, WHO grade I). However, manic symptoms have been documented to occur more frequently in right frontal tumors. Early neuroimaging and a high index of suspicion are crucial to avoid misdiagnosis and ensure timely treatment of brain tumors with psychiatric symptoms