Hemolytic Uremic Syndrome Following the Aluminum Phosphide Poisoning: A Case Report

Reza Asadzadeh; Aliashraf Mozafari; Fakhredin Taghinezhad; Fatemeh Pourrezagholi; Zahra  Khalighi

doi:10.18502/acta.v61i10.15664

Reza Asadzadeh Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran
Aliashraf Mozafari Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran
Fakhredin Taghinezhad Department of Nursing, School of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam, Iran
Fatemeh Pourrezagholi Chronic Kidney Disease Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Zahra Khalighi Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran

DOI: https://doi.org/10.18502/acta.v61i10.15664

Keywords: Aluminum phosphide poisoning; Hemolytic uremic syndrome; Acute kidney injury

Abstract

Aluminum Phosphide (ALP) is an effective, cheap, and highly toxic pesticide. ALP poisoning can have destructive effects on the human body, such as the heart, lungs, gastrointestinal tract, kidneys, and central nervous system, although all organs can be involved. We describe a 53-year-old Iranian Kurdish man with Hemolytic Uremic Syndrome (HUS) and Acute Kidney Injury (AKI). Supportive treatments such as hemodialysis and plasmapheresis were performed. After 23 days of hospitalization, the patient fully recovered and was discharged. Thrombotic microangiopathy such as HUS should be considered in patients with ALP toxicity that has a genetic defect in complement proteins. Combined use of hemodialysis and plasmapheresis improve outcomes in these patients.