CD4 Cell Counts, Lipid Profile, and Oral Manifestations in HIV-Infected and AIDS Patients

Koduri  Sridevi1; Saka  Malathi; Chalapathi  KV; Chowdary   Nagarjuna G; M  Gayathri; G  Eswar Chand6; Abhishek Singh   Nayyar

doi:10.18502/fid.v16i6.3443

Koduri Sridevi1
Saka Malathi
Chalapathi KV
Chowdary Nagarjuna G
M Gayathri
G Eswar Chand6
Abhishek Singh Nayyar

DOI: https://doi.org/10.18502/fid.v16i6.3443

Keywords: CD4 Cell Counts; Lipids; Oral Manifestations; HIV Infections; Acquired Immunodeficiency Syndrome

Abstract

Objectives: The present study aimed to evaluate CD4 cell counts, lipid profile, and oral manifestations in human immunodeficiency virus (HIV)-infected and acquired immune deficiency syndrome (AIDS) patients and their correlation with seronegative controls.

Materials and Methods: In this cross-sectional, hospital-based study, there were three groups of subjects: group A consisting of 500 healthy patients (controls), group B composed of 500 HIV-infected patients, and group C comprised of 500 AIDS patients based on their CD4 cell counts. CD4 cell counts were assessed using the CyFlow counter. Lipid profile was evaluated with the Erba EM 360 analyzer.

Results: The results were statistically significant for CD4 cell counts (P<0.001). The levels of total cholesterol (TC) and low-density lipoproteins (LDLs) were significantly decreased while triglycerides (TGs) and very-low-density lipoproteins (VLDLs) were significantly increased in AIDS patients compared to the controls and HIV-infected patients. Various results were obtained regarding oral manifestations with different levels of significance.

Conclusion: CD4 cell counts, TC, LDLs, TGs, and VLDLs were significantly changed in HIV-infected and AIDS patients compared to the controls.