Bonding to Molar-Incisor Hypomineralization Affected Teeth: A Scoping Review of Adhesive Strategies, In Vitro Performance, and Clinical Outcomes

Fatemeh Mahmoodi  Khorandi; Shayan  Moradi; Golnaz  Tayebi; Tabassom  Hooshmand

doi:10.18502/fid.v23i16.21619

Fatemeh Mahmoodi Khorandi Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Shayan Moradi Department of Dental Biomaterials, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
Golnaz Tayebi Department of Dental Biomaterials, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
Tabassom Hooshmand Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran

DOI: https://doi.org/10.18502/fid.v23i16.21619

Keywords: Hypomineralization; Bonding; Composite Resins; Glass Ionomer; Dental Restoration

Abstract

Molar‑incisor hypomineralization (MIH) poses major restorative challenges due to compromised enamel and its reduced bonding capacity. This scoping review evaluated treatment options for MIH‑affected young permanent teeth following PRISMA‑ScR guidelines. A systematic search in PubMed, Cochrane, Science Direct and gray literature identified 21 eligible studies published between 2013 and 2025, including in‑vitro and clinical studies. Laboratory findings demonstrated lower bond strengths in MIH enamel compared with the sound enamel. Etch‑and‑rinse adhesives performed more reliably than that of self‑etch systems, while pretreatment procedures improved adhesion in some settings. Clinical studies showed resin‑based sealants and composites bonded with etch‑and‑rinse adhesives achieved higher retention. Glass ionomer and glass hybrid restorations offered mostly short-term success and are best used as an interim option. Investigated indirect restorations provided superior longevity in severe cases. Preventive adjuncts such as applying varnishes reduced hypersensitivity and caries risk. Finally, this review highlights the central role of adhesive performance in MIH management.