Pitfalls in the Histopathologic Diagnosis of Meningioma: Report of Three Rare Variants of Meningioma and Literature Review

Ghazaleh Shaker; Farid  Azmoudeh Ardalan; Mehdi Zeinalizadeh

doi:10.18502/crcp.v6i4.7861

Ghazaleh Shaker Department of Pathology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
Farid Azmoudeh Ardalan Department of Pathology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
Mehdi Zeinalizadeh Department of Neurological Surgery, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

DOI: https://doi.org/10.18502/crcp.v6i4.7861

Keywords: Clear cell meningioma; Microcystic meningioma; Angiomatous meningioma; Differential diagnosis

Abstract

Meningioma is a common primary tumor of the central nervous system and one of the most encountered brain tumors. Although classic histopathologic features of meningioma are relatively common and make its diagnosis straightforward, certain variants possess unusual histologic features causing diagnostic challenges. We reported three cases of clear cell meningioma, microcytic meningioma, and angiomatous meningioma report, variants with potential deceptive morphologies, and discuss their distinguishing morphologic features.