Metastatic Gastric Adenocarcinoma Cancer With a Very High Serum Carbohydrate Antigen 19-9 Level: A Case Study

Ali Reza Jafarinezhad; Neda  Aligoli Ghasemabadi

doi:10.18502/crcp.v6i1.5956

Ali Reza Jafarinezhad Department of Internal Medicine, Inflammatory Lung Disease Research Center, School of Medicine, Razi Hospital, Guilan University of Medi- cal Sciences, Rasht, Iran.
Neda Aligoli Ghasemabadi Department of Internal Medicine, Inflammatory Lung Disease Research Center, School of Medicine, Razi Hospital, Guilan University of Medi- cal Sciences, Rasht, Iran.

DOI: https://doi.org/10.18502/crcp.v6i1.5956

Keywords: Gastric adenocarcinoma; Tumor marker; Carbohydrate Antigen 19-9 (CA-19-9)

Abstract

Carbohydrate Antigen 19-9 (CA19-9) is a tumor marker for the prognosis of colorectal and pancreatic cancers. The high level of this tumor marker in gastric cancer indicates the advanced stage and peritoneal metastasis of the tumor. We reported a case of gastric cancer with an extremely high serum level of CA19-9. We also measured the serum levels of carcinoembryonic antigen and Carbohydrate Antigen 125 in the reported case. Such tumor markers manifest the progression and poor prognosis of cancer. Computed tomography data indicated several lytic and sclerotic foci in the inferior thoracic, lumbar vertebrae, and the right iliac wing, along with invasion to lymph nodes and a right adnexal mass in the reported patient. Bone marrow biopsy results revealed that carcinoma cells were predominantly composed of signet ring cell carcinoma. The patient has expired before receiving any interventions for cancer.