Post-COVID-19 Complications:A Trigger for the Onset of Depression to Treatment-Resistant Depression: A Case Report

Authors

  • Shokouh Gheibi Razi Educational and Therapeutic Psychiatric Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
  • Omid Rezaei Psychiatry Department, Psychosis Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
  • Morvarid Ahadi Psychiatry Department, Psychosis Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

DOI:

https://doi.org/10.18502/crcp.v11i1.22168

Keywords:

Depression; COVID-19; Electroconvulsive therapy; Treatment-resistant depression

Abstract

Coronavirus Disease 2019 (COVID-19) has been associated with both acute and long- term complications, spanning cardiorespiratory and neuropsychiatric domains. The neuropsychiatric sequelae may stem from immune system dysregulation, inflammatory cytokines, and psychosocial stressors, including threats to personal health, economic stability, and social standing. This case report presents a 55-year-old male with no prior psychiatric history who developed treatment-resistant depression following COVID-19 infection. The study emphasizes the psychological repercussions of the pandemic, particularly in individuals with fragile premorbid personality structures

Published

2026-08-02

Issue

Volume (11) issue (1)

Section

Articles