Cerebral Infarction Due to Calcified Amorphous Tumor: A Rare Case Report

Ghazaleh  Salehabadi; Shahla  Meshgi; Hamidreza  Pouraliakbar; Azin Alizadeh  Asl; Ali  Mohammadzadeh

doi:10.18502/crcp.v9i5.18457

Ghazaleh Salehabadi Student Research Committee, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
Shahla Meshgi Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
Hamidreza Pouraliakbar Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
Azin Alizadeh Asl Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
Ali Mohammadzadeh Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran

DOI: https://doi.org/10.18502/crcp.v9i5.18457

Keywords: Calcified amorphous tumor; Embolism; Cerebral infarction; CMR; Echocardiography

Abstract

A Calcified Amorphous Tumor (CAT) consists of calcified nodules embedded withinan amorphous fibrous material and represents an uncommon non-neoplasticintracavitary cardiac mass. In this article, we present the case of a 38-year-old Iraniangentleman who experienced a sudden loss of consciousness and right hemiparesis.Brain imaging revealed acute infarction in the left basal ganglia. Echocardiographyidentified a large heterogeneous echodensity in the posterior AV groove, with centralecholucency extending to the base of the posterior left ventricular (LV) wall and thebasal posterior mitral valve leaflet (PMVL), findings consistent with CAT.Cardiac Magnetic Resonance Imaging (CMR) demonstrated an intramural calcifiedmass with a necrotic core located in the lateral annulus of the mitral valve, extendinginto the left atrium and ventricle. The mass was deemed responsible for the cerebralinfarction, which was classified as cardioembolic. This case report highlights CalcifiedAmorphous Tumor (CAT) as a potential embolic source, underscoring the importanceof early recognition through multimodality imaging. Comprehensive management,which may include regular follow-ups or surgical intervention, is crucial for patientsdiagnosed with CAT.