Silent Thyroiditis Presented as Transient Hypothyroidism During Pregnancy: A Case Report

Mahmoud Ali  Kaykhaei; Shahin  Nosratzehi

doi:10.18502/crcp.v9i5.18453

Mahmoud Ali Kaykhaei Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran
Shahin Nosratzehi Department of Internal Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran

DOI: https://doi.org/10.18502/crcp.v9i5.18453

Keywords: Hypothyroidism; Pregnancy; Thyroiditis; Transient; Thyroid Dysfunction

Abstract

Silent thyroiditis during pregnancy is an under-recognized clinical condition and arare case, often manifesting as transient hypothyroidism. We report a 23-year-oldwoman at 8 weeks of gestation who presented with newly diagnosed hypothyroidism[TSH = 85 mIU/L (0.4–4.5), FT4 = 0.4 ng/dL (0.7–2.5), and anti-TPO = 78 IU/mL (upto 16)]. Thyroid function tests had been normal eight months prior. Levothyroxine(LT4) therapy was initiated, restoring euthyroidism. Treatment was discontinuedpostpartum, and the patient maintained normal thyroid function for over one year.Our case is unique in that silent thyroiditis occurred unusually early in pregnancyand differed from the more common postpartum cases. Silent thyroiditis should beconsidered in pregnancy-related hypothyroidism, particularly when prior thyroidfunction was normal. Prompt diagnosis and treatment can prevent adverse maternaland fetal outcomes