Emerging Resistance in Chlamydia Requires Surveillance and Reassessment

Abstract

Background: Chlamydia trachomatis remains one of the most common sexually transmittedinfections (STIs) globally, often asymptomatic but capable of causing serious reproductivecomplications if left untreated. While azithromycin and doxycycline have traditionally been highlyeffective first-line treatments, recent evidence suggests a growing concern over reduced antibioticefficacy and potential resistance.

Conclusion: This commentary highlights emerging clinical patterns, the need for surveillance, andthe importance of reassessing treatment strategies to mitigate a future public health challenge