Molecular Diagnosis of Chlamydia trachomatis in Women with Frequent Abortions

Haniyeh  Bashi Zadeh Fakhar; Sara Kazemirad; Melika Jalalian; Sahar Rabie Pour

doi:10.18502/jmb.v12i2.15621

Haniyeh Bashi Zadeh Fakhar Department of Human Genetics, Science and Research Branch, Branch, Islamic Azad University, Tehran, Iran
Sara Kazemirad Department of Cell and Molecular Sciences, Faculty of Advanced Sciences & Technology ,Tehran Medical Science, Islamic Azad University, Tehran, Iran.
Melika Jalalian Department of Cell and Molecular Sciences, Faculty of Advanced Sciences & Technology ,Tehran Medical Science, Islamic Azad University, Tehran, Iran.
Sahar Rabie Pour Department of Laboratory Science, Chalous Branch, Islamic Azad University, Chalous, Iran.

DOI: https://doi.org/10.18502/jmb.v12i2.15621

Keywords: Abortions, Chlamydia trachomatis, Diagnostic, PCR.

Abstract

Background: Chlamydia trachomatis is the commonest cause of bacterial sexually transmitted infections. This research aimed at scrutinizing the Chlamydia trachomatis screening tests with vaginal samples and at investigating the correlation between Chlamydia trachomatis infection and the abortion incidence.

Methods: The current Cross sectional study was done at gynecology clinic of Razi Hospital in Chalus, Iran between August 2017 and January 2018. Fifty vaginal swabs were collected and detecting C. trachomatis DNA was done. Chi-square test and Independent t-test compared the variables. P <0.001 was significant

Results: The total C. trachomatis infection prevalence was 5(10%) in endocervical swabs. A significant difference was found between duration of sexual activity and Chlamydia infection. No significant difference was detected between detection of Chlamydia l and abnormal vaginal discharged.

Conclusion: Screening for Chlamydia trachomatis infection of the women experiencing a miscarriage should be done and, if positive, they should be treated to inhibit recurrent miscarriages.