Maternal Urinary Tract Infection: Is It Associated With Neonatal Urinary Tract Infection?

Huseyin Bilgin; Emine Esin Yalinbas; Ilknur Elifoglu; Sahinde Atlanoglu

doi:10.18502/jfrh.v15i1.6067

Huseyin Bilgin Department of Pediatrics, Evliya Celebi Research and Training Hospital, Kutahya, Turkey
Emine Esin Yalinbas Department of Pediatrics, Division of Neonatology, School of Medicine, Dumlupinar University, Kutahya, Turkey
Ilknur Elifoglu Department of Pediatrics, School of Medicine, Dumlupinar University, Kutahya, Turkey
Sahinde Atlanoglu Department of Radiology, Evliya Celebi Research and Training Hospital, Kutahya, Turkey

DOI: https://doi.org/10.18502/jfrh.v15i1.6067

Keywords: Urinary Tract Infection; Pregnancy; Newborn; Culture; Ultrasonography

Abstract

Objective: Maternal urinary tract infection is associated with intrauterine growth restriction, preterm delivery and low birth weight. The purpose of this study was to evaluate whether maternal urinary tract infection is related to neonatal urinary tract infection.

Materials and methods: The present prospective study included 230 singleton neonates. The participants were divided into two groups based on in utero exposure to maternal urinary tract infections. The study group (exposure to maternal urinary tract infection) included 115 neonates and the control group (without exposure to maternal urinary tract infection) included 115 healthy neonates. Physical examination, urinalysis, urine culture and urinary system ultrasonography were carried out for all neonates.

Results: There were 153 deliveries by cesarean section and 77 vaginal births. There was no statistically significant difference between the groups in terms of gender distribution, maternal age, birth weight, mode of delivery, gravida and gestational age. Although the difference was not significant, the incidence of low birth weight and preterm delivery were higher in the study group in comparison to that in the control group. There was a statistically significant higher rate of neonatal urinary tract infection in the study group compared with control group (25.2% vs. 7.8%, p<0.001). The most commonly discovered pathogens were Escherichia coli, followed by Klebsiella spp., Proteus spp., and Serratia spp. in the study group.

Conclusion: The results of this study showed that the presence of maternal urinary tract infection may contribute to increased urinary tract infection frequency in the neonatal period. Neonates at risk for a urinary tract infection should be regularly monitored due to nonspecific clinical presentation.