Small Cell Neuroendocrine Cervical Carcinoma: A Case Report

Malihe   Hasanzadeh; Nooshin Babapour; Marjaneh  Farazestanian; Farzaneh   Hashem Niay Torshizi

doi:10.18502/jfrh.v14i4.5212

Malihe Hasanzadeh
Nooshin Babapour
Marjaneh Farazestanian
Farzaneh Hashem Niay Torshizi

DOI: https://doi.org/10.18502/jfrh.v14i4.5212

Keywords: Small Cell Neuroendocrine Tumor; Cervical Carcinoma; Chemoradiotherapy; Chemotherapy

Abstract

Objective: Small cell neuroendocrine cervical carcinoma is a neuroendocrine tumor with the great aggravation that comprises 0.5 to 3 percent of cervical tumors and progresses rapidly with early lymphogenous and hematogenous metastases.

Case report: We reported a 40 years old woman with cervical cancer in stage IB2 that had radical hysterectomy with mistaken diagnosis of squamous cervical cancer. The disease has progressed after 50 days of surgery with a 6 cm tumor in vaginal cuff; review of pathology demonstrated small cell neuroendocrine cervical carcinoma.

Conclusion: Recognition of this separate histopathological entity with IHC analysis is important. Chemoradiotherapy and multimodality therapeutic approaches could improve the survival rates.