Role of Bariatric Surgery in Patients With Endometrial Cancer: A Case Report and  Review of Literature

Maliheh Arab; Azadeh Jafari  Ashtiani; Behnaz Ghavami; Behnaz Nouri; Giti Noghabaei; Masoomeh Raoufi

doi:10.18502/jfrh.v18i2.15938

Maliheh Arab Department of Gyneco-oncology, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Azadeh Jafari Ashtiani Department of Gyneco-oncology, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Behnaz Ghavami Obstetrics and Gynecology Department, Arash Women’s Hospital, Tehran University of Medical Sciences, Tehran, Iran
Behnaz Nouri Department of Obstetrics and Gynecology, Shohada Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Giti Noghabaei Imam Hossein Hospital, Iran University of Medical Sciences, Tehran, Iran
Masoomeh Raoufi Department of Radiology, School of Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

DOI: https://doi.org/10.18502/jfrh.v18i2.15938

Keywords: Endometrial Neoplasms; Morbid Obesity; Bariatric Surgery

Abstract

Objective: The standard surgery for endometrial cancer can be deferred in some situations, including morbid obesity, comorbidities, and the patient's desire for fertility. One of the options to improve patients' circumstances is bariatric surgery.

Case report: This study presented two patients with stage IA, grade I endometrioid endometrial adenocarcinoma. Both patients had morbid obesity and had comorbidities. In case 1, because of fertility preservation, and in case 2, because of severe comorbidities, hormone therapy was started, followed by bariatric surgery after counseling patients. Both patients had acceptable changes in body mass index during follow-up, so cancer surgery through laparoscopy was done. Both patients did not need adjuvant therapy; months after cancer surgery, there is no recurrence, and their body mass index is also decreasing.

Conclusion: Bariatric surgery can improve outcomes in patients with morbid obesity who suffer endometrial cancer.