Association between Proteinuria and Sleep in the Azar Cohort Population: A Cross-Sectional Study

  • Farahnoosh Farnood Assistant Professor, Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  • Elnaz Faramarzi Associate Professor, Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  • Aysouda Ghanizadegan Physician, Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  • Seyyedeh Mina Hejazian MSc., Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  • Sepideh Zununi Vahed Associate Professor, Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  • Mohammadreza Ardalan Professor, Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Keywords: Proteinuria, Azar cohort, Sleep disorder, Chronic kidney disease

Abstract

Background and Objectives: Sleep disorders are common issues in people's health and can be related to metabolic and kidney diseases. Studies have shown that the relationship between proteinuria and sleep disorders can be modified. Since this relationship has not been investigated in Iranian populations, this study examined the relationship between proteinuria and sleep in the Azar cohort population.

Methods: This cross-sectional study used data from the Azar cohort study with a population of 15,000. Based on the study's inclusion and exclusion criteria, 105 patients with proteinuria were selected. After age and sex matching, 420 patients without proteinuria were included in the control group. The patients' sleep patterns were assessed based on a designed questionnaire, and the results were compared between the two groups.

Results: None of the sleep factors significantly differed between the two groups with and without proteinuria (P>0.05). Moreover, the mean weight, waist circumference, systolic blood pressure, diastolic blood pressure, and body mass index (BMI) were significantly different in the two groups (P<0.001).

Conclusion: There was no significant relationship between proteinuria and sleep in the Azar cohort population. However, the weight, BMI, waist circumference, and systolic and diastolic blood pressure significantly differed between people with and without proteinuria.

Published
2025-09-06
Section
Articles