National Consensus Guideline on Diagnosis and Management of Predominantly Antibody Deficiencies

Reza  Yazdani; Samaneh  Abdolahzade; Parisa  Ashournia; Aida  Askarisarvestani; Sima  Bahrami; Maryam  Behfar; Zahra  Daneshmandi; Mohammad Hassan  Bemanian; Taher  Cheraghi; Kian  Darabi; Sepideh  Darougar; Samaneh  Delavari; Sarehsadat  Ebrahimi; Shabnam  Eskandarzadeh; Golnaz  Eslamian; Narges  Eslami; Shahrzad  Fallah; Morteza  Fallahpour; Saba  Fekrvand; Ali  Haghbin; Amir Ali  Hamidieh; Zohre  Hassanpoor; Zahra Hamidi  Esfahani; Tolue  Mahdavi; Mehrnaz  Mesdaghi; Homa Hatefi  Minaei; Majid  Marjani; Shahla  Mirazizi; Mohammadreza  Modaresi; Mahshid  Movahedi; Mohammamd  Nabavi; Mojtaba  Ranjbar; Anahita  Razaghian; Mohammad  Saberi; Mahnaz  Sadeghi-Shabestari; Mitra  Sahragard; Fereshte  Salami; Sahar  Seraj; Seyedehshabnam  Seyedsalehi; Alireza  Shafiei; Roya  Sherkat; Reza  Shiari; Sima  Shokri; Saman  Tavakoli; Ahmad  Vosughimotlagh; Niloufar  Yazdanpanah; Vahid  Ziaee; Nima  Rezaei

doi:10.18502/igj.v7i2.17850

Reza Yazdani Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Samaneh Abdolahzade Department of Pediatric Disease, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Parisa Ashournia Division of Allergy and Clinical Immunology, Department of Pediatrics, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Aida Askarisarvestani Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Assistant Professor, Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Sima Bahrami Department of Allergy and Clinical Immunology, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Maryam Behfar Pediatric Cell and Gene Therapy Research Centre, Gene, Cell & Tissue Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Zahra Daneshmandi Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad Hassan Bemanian Department of Allergy and Clinical Immunology, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Taher Cheraghi Department of Pediatrics, 17th Shahrivar Children's Hospital, Guilan University of Medical Sciences, Rasht, Iran
Kian Darabi Department of Allergy and Clinical Immunology, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Sepideh Darougar Department of Pediatrics, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
Samaneh Delavari Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Sarehsadat Ebrahimi Division of Allergy and Clinical Immunology, Department of Pediatrics, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Shabnam Eskandarzadeh Department of Pediatrics, Pediatric Health Center, Tabriz University of Medical Sciences, Tabriz, Iran
Golnaz Eslamian Department of Allergy and Clinical Immunology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Narges Eslami Department of Allergy and Clinical Immunology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Shahrzad Fallah Immunology and Allergy Department, Mofid Children's Hospital Shahid Beheshti University of Medical Sciences, Tehran, Iran
Morteza Fallahpour Department of Allergy and Clinical Immunology, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Saba Fekrvand Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Ali Haghbin Department of Pediatrics, North Khorasan University of Medical Sciences, Bojnurd, Iran
Amir Ali Hamidieh Pediatric Cell and Gene Therapy Research Centre, Gene, Cell & Tissue Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Zohre Hassanpoor Allergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Zahra Hamidi Esfahani Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Tolue Mahdavi Department of Allergy and Clinical Immunology, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Mehrnaz Mesdaghi Department of Allergy and Clinical Immunology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Homa Hatefi Minaei Dorsa Pharmaceutical Co, Alborz, Iran
Majid Marjani Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahla Mirazizi Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Shariati Street, Kermanshah, Kermanshah, Iran
Mohammadreza Modaresi Pediatric Pulmonary Disease and Sleep Medicine Research Center, Pediatric Center of Excellence, Children's Medical Center, Tehran, Iran.
Mahshid Movahedi Division of Allergy and Clinical Immunology, Department of Pediatrics, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Mohammamd Nabavi Department of Allergy and Clinical Immunology, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Mojtaba Ranjbar Children’s Medical Center, Pediatric Center of Excellence, Tehran, Iran
Anahita Razaghian Division of Allergy and Clinical Immunology, Department of Pediatrics, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Mohammad Saberi Department of Medical Genetics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Mahnaz Sadeghi-Shabestari Department of Immunology and Allergy, Tabriz University of Medical Sciences, Tabriz, Iran
Mitra Sahragard Department of Immunology and Allergy, Tabriz University of Medical Sciences, Tabriz, Iran
Fereshte Salami Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Ira
Sahar Seraj Department of Immunology and Allergy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Seyedehshabnam Seyedsalehi Abuzar Children’s Medical Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Alireza Shafiei Department of Immunology, Bahrami Hospital, Tehran University of Medical Sciences, Tehran, Iran
Roya Sherkat Immunodeficiency Diseases Research Center, Isfahan University of Medical Sciences , Isfahan , Iran
Reza Shiari Division of Pediatric Rheumatology, Department of Pediatrics, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Sima Shokri Department of Allergy and Clinical Immunology, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
Saman Tavakoli Department of Pediatric, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Ahmad Vosughimotlagh Immunology and Allergy Department, Mofid Children's Hospital Shahid Beheshti University of Medical Sciences, Tehran, Iran
Niloufar Yazdanpanah Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Vahid Ziaee Pediatric Rheumatology Research Group, Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
Nima Rezaei Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran

DOI: https://doi.org/10.18502/igj.v7i2.17850

Keywords: Herbal Medicine; Probiotics ; Asthma; Respiratory Disorder

Abstract

At present, a national consensus or guideline for diagnosing and managing patients suspected of havingpredominantly antibody deficiencies (PADs) is lacking. This consensus is written based on a combinationof scientific literature and comments from the expert panel of Iranian immunologists. A group of clinicalimmunologists reviewed the current consensus, presented their comments at a meeting titled 'First Meetingon the Diagnosis of Inborn Errors of Immunity (IEI) by IEI Experts,' and agreed on this consensus. Thisconsensus guideline provides recommendations on the diagnosis, antimicrobial prophylaxis, managementof clinical manifestations, and immunoglobulin replacement therapy (IgRT) for patients with PAD.