Multiple Sclerosis and its Pathophysiology: A Narrative Review

Ali   Alizadeh Khatir; Seyed Mohammad Masood  Hojjati; Alijan  Ahmadi Ahangar; Hoda  Naghshineh; Payam   Saadat

doi:10.18502/tbsrj.v2i2.3757

Ali Alizadeh Khatir
Seyed Mohammad Masood Hojjati
Alijan Ahmadi Ahangar
Hoda Naghshineh
Payam Saadat

DOI: https://doi.org/10.18502/tbsrj.v2i2.3757

Keywords: Multiple Sclerosis, Pathophysiology, Nervous system

Abstract

Multiple sclerosis (MS) is one of the most important debilitating diseases in which the myelin sheaths of nerve cells in the brain and spinal cord are damaged. In this review, we aimed to review the pathophysiology of MS. This impairment causes ability disorder of the parts of the nervous system which are responsible for communication, leading to different symptoms including physical and psychological problems. This study was conducted through a Narrative review using keywords including Multiple Sclerosis, Epidemiology through Search in International Scientific Databases, including: PubMed, Web of Science, Google Scholar and Scopus, and Persian scientific databases including: Barakatkns Knowledge System, Academic Jihad Database, Iranian Medical Library (Medlib), Magiran Database, Knowledge Reference (Civilica), and a search was done on the World Health organization website. In this review study, using keywords such as "pathophysiology" and "multiple sclerosis".