Analysis of Adverse Reactions of Blood Transfusion and Discus-sion of Influencing Factors in Linyi Area from 2013 To 2020

Xiuping  Zhang; Yanli  Zhang; Yanli  Zhang; Cao Qi; Chunling  Ma

doi:10.18502/ijph.v50i7.6631

Xiuping Zhang Department of Blood Supply, Linyi City Central Bloodbank, Linyi, Shandong 276000, P.R. China
Yanli Zhang Birth Defect Study Laboratory, Linyi Maternal and Child Health Care Hospital, Linyi, Shandong 276000, P.R. China
Yanli Zhang Birth Defect Study Laboratory, Linyi Maternal and Child Health Care Hospital, Linyi, Shandong 276000, P.R. China
Cao Qi Birth Defect Study Laboratory, Linyi Maternal and Child Health Care Hospital, Linyi, Shandong 276000, P.R. China
Chunling Ma Birth Defect Study Laboratory, Linyi Maternal and Child Health Care Hospital, Linyi, Shandong 276000, P.R. China

DOI: https://doi.org/10.18502/ijph.v50i7.6631

Keywords: Blood transfusion; Allergic reactions; Fever; Blood products

Abstract

Background: We aimed to explore the influencing factors of clinical adverse blood transfusion reactions, to provide theoretical basis and support for clinical safe blood transfusion, and to minimize the occurrence of adverse blood transfusion reactions.

Methods: The method was to retrospectively analyze the report of adverse blood transfusion reports from 6 hospitals in Linyi area, Shandong, China to the blood station in Linyi City center from 2013 to 2020. We aimed to classify factors, analyze the occurrence of adverse transfusion reactions, and discuss the correlation between the occurrence of adverse transfusion reactions and the above factors.

Results: Overall, 248 patients (77.98%) had a history of blood transfusion. The difference between this group and the group with no history was statistically significant (P<0.05). The incidence of adverse transfusion reactions in middle-aged and elderly patients was relatively high, especially for those over 50 yr old, with an adverse reaction of 135, for example, the proportion reached 42.45%. In addition, a retrospective analysis found that the occurrence of adverse transfusion reactions was mostly concentrated from Mar to Sep, a total of 228 cases, accounting for 71.69% of all adverse reactions, which was the highest incidence of adverse transfusion reactions.

Conclusion: The main adverse reactions of transfusion were allergic reactions, followed by non-hemolytic febrile reactions, mainly caused by transfusion of suspended red blood cells.