Impact of Inadequate Nutrition in Lung Transplant Recovery: A Meta-Analysis

Xu  Cao; Chenxia  Liu; Qiuyue  Liu; Jian  Gao; Yan  Wang; Feng  Yang; Feng  Yang

doi:10.18502/ijph.v54i3.18239

Xu Cao Department of Healthcare Ward, Peking University People’s Hospital, Peking, China
Chenxia Liu Department of Healthcare Ward, Peking University People’s Hospital, Peking, China
Qiuyue Liu Department of Healthcare Ward, Peking University People’s Hospital, Peking, China
Jian Gao Department of Thoracic Surgery, Peking University People's Hospital, Peking, China
Yan Wang Department of Healthcare Ward, Peking University People’s Hospital, Peking, China
Feng Yang Department of Thoracic Surgery, Peking University People's Hospital, Peking, China
Feng Yang Department of Thoracic Surgery, Peking University People's Hospital, Peking, China

DOI: https://doi.org/10.18502/ijph.v54i3.18239

Keywords: Lung transplant; Hospital; Intubation post-lung transplant; Frail; All-cause mortality; Intensive care

Abstract

Background: We aimed to appraise and compare the impact of inadequate nutrition in lung transplant recovery.

Methods: Based on the inspection of the meta-analysis data, the odds ratio (OR) and mean difference (MD) with 95% confidence intervals (CIs) were derived by dichotomous random or fixed effect models. 6 papers with 1399 lung transplant who were available between 2020 and 2024 were comprised in this meta-analysis.

Results: Frail had significantly higher hospital length of stay (MD, 2.80; 95% CI, 1.80-3.80, P< 0.001), and all-cause mortality (OR, 2.33; 95% CI, 1.40-3.87, P=0.001) compared to non-frail in subjects with lung transplant. However, no significant difference was found between frail and non-frail in intubation post-lung transplant (MD, 7.00; 95% CI, -17.52-31.52, P=0.58), and intensive care unit length of stay (MD, -1.70; 95% CI, -4.53- 1.14, P=0.24) in subjects with lung transplant.

Conclusion: Using frail had significantly higher hospital length of stay, and all-cause mortality, however, no significant difference was found in intubation post-lung transplant, and intensive care unit length of stay compared to non-frail in subjects with lung transplant However, given that comparisons comprised a small number of studies, attention ought to be given to their values.