Prevalence and Distribution of Osteopenia in Chinese  Population: A System Review and Meta-Analysis

Yanpeng  Wang; Yinzhen  Zhang; Lanbo  Zhao; Guochen  Wang; Chengan  Yang; Changwei  Zhao; Wenhai  Zhao

doi:10.18502/ijph.v51i11.11161

Yanpeng Wang Department of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130117, China
Yinzhen Zhang Department of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130117, China
Lanbo Zhao Department of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130117, China
Guochen Wang Department of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130117, China
Chengan Yang Department of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130117, China
Changwei Zhao Department of Orthopedics, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130021, China
Wenhai Zhao Department of Orthopedics, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130021, China

DOI: https://doi.org/10.18502/ijph.v51i11.11161

Keywords: Osteopenia; Meta-analysis; Prevalence; China; Osteoporosis

Abstract

Background: The number of patients with osteoporosis ranks first in the world in China and as a precursor state of osteoporosis, the number and incidence of osteopenia are much higher than that of osteoporosis. This meta-analysis was conducted to evaluate the incidence and distribution of osteopenia in adults in mainland of China over 10 years to provides reference for the early prevention of osteoporosis and policymaking.

Methods: Relevant data were extracted from the databases including CNKI, Wanfang, VIP, Web of Science, PubMed, EMBASE, and Medline about the surveys on osteoporosis and bone loss from 2010 to 2021 by searching. The random effects model was adopted for Meta-analysis, and the funnel plot was used to test publication bias.

Results: Forty-seven literatures were included in this study, covering 27 provinces and 38 regions in the mainland of China, with the study of 135,688 cases, showing that the prevalence of osteopenia in adults in the past decade was 28.3%(95% CI 24-33%), aged 40~60 yr old , reaching the highest level. The incidence of osteopenia in males was higher than that in females (P<0.05), without significant difference in south and north China.

Conclusion: There is a large population with osteopenia in China, especially middle-aged population, both men and women should pay attention to osteopenia to delay its further progression.