Diagnostic Accuracy of Fine Needle Aspiration Cytology for Breast Lump by Yokohama System for Reporting and Its Correlation with Histomorphology

Nikita  Taur; R. R.  Soni; A T  Deshmukh; Sonal  Chaukade

doi:10.18502/bccr.v16i1.18751

Nikita Taur Dr. Panabrao Deshmukh Memorial Medical College, Amravati, India
R. R. Soni Dr. Panabrao Deshmukh Memorial Medical College, Amravati, India
A T Deshmukh Dr. Panabrao Deshmukh Memorial Medical College, Amravati, India
Sonal Chaukade Dr. Panabrao Deshmukh Memorial Medical College, Amravati, India

DOI: https://doi.org/10.18502/bccr.v16i1.18751

Keywords: Pathology, histomorphology, diagnosis

Abstract

Background: The International Academy of Cytology Yokohama System has cre-ated a standardized method of describing breast cytology by grouping them into 5categories: inadequate, benign, atypical, suspicious, and malignant. To validate thelikelihood of cancer in the various categories, several investigations have been under-taken at various institutions as a mandate. Aim: The main objective of the researchis to identify the accuracy of fine needle aspiration cytology for breast lumps by theYokohama system for reporting and its correlation with histopathology.

Methodology: The present study was a retrospective study performed over 8 months.The Yokohama system performs FANCs for breast lumps. Whenever accessible, his-topathological diagnoses were also retrieved. Statistical Analysis Used: Sensitivity,specificity, PPV, NPV, and diagnostic accuracy were estimated using a histologicaldiagnosis as the gold standard for each of the five categories.

Results: Out of 200 cases 106 had histopathological concordance. Five categories- insufficient, benign, atypical, suspicious, and malignant of the IAC Yokohama sys-tem were 1.00%, 62.50%, 4.50%, 1.50%, and 30.50%, Category1(1%), category2 (62.5%),category3 (4.5%), category4(1.5%), category5 (30.5%). When malignant, suspicious,and unusual cases were taken into account as positive test findings, the highest levelof sensitivity (90.60%) was attained. The maximum specificity (100%) was seen whenonly malignant patients were taken into account as positive test findings, but thehighest diagnostic accuracy (96.22%) was shown when the malignant and suspectcategories were taken into account as positive test results.

Conclusion: FNAC using the Yokohama system for reporting is an accurate diagnos-tic tool for breast lumps. The system provides a standardized framework for reportingFNAC findings, and studies have reported high sensitivity and specificity rates fordiagnosing breast lumps using FNAC. Therefore, FNAC can be used with histomor-phology to ensure accurate diagnosis and appropriate management of breast lumps