Effect of Enhanced Recovery After Surgery vs. Traditional Postoperative Care in Patients with Endometriosis: A Retrospective Cohort Study

Authors

  • Saman Mohamadipour Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran
  • Rojin Sarallah Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran
  • Khadijeh Shadjoo Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran
  • Morvarid Ahmad Beigi Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran
  • Atefeh Gorgin Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran
  • Roxana Kargar Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran
  • Salar Javanshir Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran
  • Roya Padmehr Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran

DOI:

https://doi.org/10.18502/jri.v27i2.23148

Keywords:

Colorectal surgery, Endometriosis, Enhanced recovery after surgery, Length of stay, Postop-erative care, Treatment outcome.

Abstract

Background: Enhanced Recovery After Surgery (ERAS) may improve recovery after bowel surgery for deep endometriosis, but disease-specific evidence remains limited. In this study, ERAS was compared with traditional care.

Methods: This retrospective cohort included 150 women undergoing laparoscopic discoid excision or segmental resection at Avicenna Fertility Clinic, Tehran, from December 2020 to December 2021 (75 per group). Outcomes were hospital stay, return to activities, fever, and 30-day rehospitalization. Groups were compared with t-tests, chi-square tests, or Fisher exact tests. Crude odds ratios (ORs), risk differences (RDs), and 95% confidence intervals (CIs) were calculated.

Results: Chief complaints differed between groups (p<0.001). ERAS was associated with discharge within 1-3 days (85.3% vs. 17.3%; RD, 68.0 percentage points; OR, 27.75; 95%CI, 11.56-66.61) and complete return to activities within 2 weeks (94.7% vs. 62.7%; RD, 32.0 points; OR, 10.57; 95%CI, 3.48-32.11). Fever (8.0% vs. 1.3%; OR, 6.43; 95%CI, 0.76-54.82) and rehospitalization (4.0% vs. 1.3%; OR, 3.08; 95%CI, 0.31-30.34) were not significantly different.

Conclusion: These findings are suggestive rather than causal and require confirmation in prospective multicenter studies with verified adjusted analyses and longer follow-up.

Published

2026-11-01

Issue

Section

Articles