Evaluation of the Safety of Ovarian Preservation at Early Stage of Endometrial Cancer in Premenopausal Women

Elham   Shirali; Mitra   Modarres Gilani; Fariba   Yarandi; Omid  Hemmatian; Azar  Ahmadzadeh; Zohre   Kazemi; Marjan   Ghaemi

doi:10.18502/jimc.v3i4.5191

Elham Shirali
Mitra Modarres Gilani
Fariba Yarandi
Omid Hemmatian
Azar Ahmadzadeh
Zohre Kazemi
Marjan Ghaemi

DOI: https://doi.org/10.18502/jimc.v3i4.5191

Keywords: Endometrial neoplasms, Hysterectomy, Fertility preservation, Salpingo-oophorectomy

Abstract

Background: Endometrial cancer usually occurs at postmenopause stage of life but its incidence in younger patients is increasing in the last decades. The objective of the study was to evaluate the ovarian preservation in the early stage of endometrial cancer.

Methods: In this cross-sectional study, 174 patients with endometrial cancer who underwent Total Abdominal Hysterectomy (TAH) and Bilateral Salpingo-oophorectomy in 5 years were included.

Results: The results showed that 51.1% of the patients were at stage IA, 28.7% at stage IB, 6.9% at stage II, 11.5% at stage III and 1.7% at stage IV of endometrial cancer when they underwent surgery. One patient (1.12%) at stage IA of endometrial cancer, one patient (2%) at stage IB and one patient (8.3%) at stage II had micrometastasis in ovaries, and 8 patients (40%) at stage III and 2 patients (66.6%) at stage IV had micrometastasis and co-existing tumor.

Conclusion: In conclusion, findings revealed the high safety of ovarian preservation in endometrial cancer at earlier stages of the endometrial cancer with low risk of ovarian involvement.