The Relationship between Type D Personality and Blood Groups Subtypes, and Medication Adherence in Iranian Patients with Type II Diabetes Mellitus

  • Mahsa Dastjerdi School of Medicine, Islamic Azad University, Najafabad Branch, Isfahan, Iran
  • Sima Sabbagh Isfahan Clinical Toxicology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  • Maryam Ghasemi Aliabadi School of Medicine, Islamic Azad University, Najafabad Branch, Isfahan, Iran
  • Sahar Shafiee Isfahan Clinical Toxicology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  • Mehdi Najarzadegan School of Medicine, Islamic Azad University, Najafabad Branch, Isfahan, Iran
  • Sara Niknam Isfahan Clinical Toxicology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  • Roqayeh Aliyari Center for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran
  • Rokhsareh Meamar Isfahan Clinical Toxicology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Keywords: ABO blood-group system, Blood glucose, Diabetes mellitus Type 2, Glycated hemoglobin, Logistic models, Medication adherence, Type D personality

Abstract

Background: The aim of this study was to investigate the relationship between blood groups and personality types, and medication adherence in Type 2 Diabetes Mellitus (T2DM).  

Methods: 302 patients with T2DM were considered in the study. Their sociodemographic information and medical history were recorded. Type D personality and medical adherence were checked using DS-14 and MMAS-8 questionnaires, respectively. Blood samples were obtained from the patients to determine the types of ABO blood groups, HbA1c, fasting blood sugar and lipid profile.

Results: No significant association was found between the patients’ characteristics including demographic and laboratory information and medical adherence to treatment. However, a significant difference in medical adherence was observed between patients with type D personality. According to logistic regression model, patients with type D [OR: 6.23, (95%CI: 2.34-16.55, p<0.001] had better adherence to medication, while the blood groups was not associated with medical adherence to treatment.

Conclusion: Type D personality cannot impair medical adherence in these patients. There was an association between type D personality and the ABO blood group, but the ABO blood group was not related to medical adherence.

Published
2026-04-11
Section
Articles