Effect of Irrigation Fluid Temperature on Hypothermia and Complications in TURP Patients Under Spinal Anesthesia: A Randomized Clinical Trial

  • Hossein Khoshrang Anesthesiology Research Center, Department of Anesthesiology, Alzahra Hospital, Guilan University of Medical Sciences, Rasht, Iran
  • Samaneh Ghazanfar Tehran Anesthesiology Research Center, Department of Anesthesiology, Alzahra Hospital, Guilan University of Medical Sciences, Rasht, Iran
  • Maryam Shakiba Department of Biostatics and Epidemiology, School of Health, Guilan University of Medical Sciences, Rasht, Iran
  • Mohammad Sadegh Foroughifar Anesthesia Research Center, Alzahra Hospital, Guilan University of Medical Sciences, Rasht, Iran
  • Ali Hamidi Madani Urology Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
  • Samaneh Esmaeili Urology Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
  • Mohaya Farzin Razi Clinical Research Development Unit, Guilan University of Medical Sciences, Rasht, Iran
  • Soghra Khalili Kisomi Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
Keywords: Hypothermia, Irrigation fluid, Spinal anesthesia, Transurethral resection of prostate (TURP)

Abstract

Background: Hypothermia during surgical procedures increases the risk of complications. This study aimed to compare the effects of Irrigation Fluid (IF) temperature on hypothermia, hemodynamic changes, and complications in patients undergoing Transurethral Resection of the Prostate (TURP) surgery under Spinal Anesthesia (SA).

Methods: In this double-blind clinical trial, 76 patients scheduled for TURP surgery were randomly assigned to two groups. The first group received warm IF heated to 37°C, while the second group received IF at room temperature. Body temperature and hemodynamic parameters were measured at five time points: upon entering the operating room (T0), after spinal anesthesia (T1), at the start of surgery (T2), at the end of surgery (T3), and during recovery (T4).

Results: In evaluating the trend of core mean body temperature changes, there was a statistically significant difference over the study period (T0-T4) in each group (p<0.001). A significant difference in mean body temperature between the two groups was observed at T2 and T3 (p<0.05), indicating higher body temperatures in group one. Additionally, there was a statistically significant difference between the two groups in terms of shivering, the need for pethidine injection, and blood product transfusion. However, no statistically significant difference was found between the groups in terms of the trends of changes in hemodynamic parameters over the study period (T0-T4).

Conclusion: Using IF heated to body temperature was associated with a lower incidence of hypothermia, reduced shivering, and fewer blood transfusions compared to room temperature IF during TURP surgery.

Published
2025-05-31
Section
Articles