Verifying Extra-Pulmonary Manifestation of COVID-19 in Firoozgar Hospital in 2020

Azadeh Mottaghi; Maryam Roham; Mahin  Jamshidi Makiani; Mitra Ranjbar; Meysam Abolmaali; Elham Rafie; Neda Rahimian

doi:10.18502/jimc.v5i3.10949

Azadeh Mottaghi Research Center for Prevention of Cardiovascular diseases, Institute of Endocrinology Metabolism, Iran University of Medical Sciences, Tehran, Iran
Maryam Roham Department of Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran
Mahin Jamshidi Makiani Department of Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran
Mitra Ranjbar Department of Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran
Meysam Abolmaali Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran
Elham Rafie Department of Internal Medicine, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
Neda Rahimian Department of Internal Medicine, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

DOI: https://doi.org/10.18502/jimc.v5i3.10949

Keywords: COVID-19, SARS-CoV-2, Coronavirus, Gastrointestinal symptom, Neurological symptom

Abstract

Background: COVID-19 is a newly emerging disease that causes a pandemic situation in the world. Coronavirus can enter into the body in several ways and it damages other organs of the body in addition to the respiratory system. This study aimed at verifying extra-pulmonary manifestation of COVID-19.

Methods: The present study was conducted as cross-sectional in a single center from March 1 to May 1 2020 at Firoozgar educational Hospital in Tehran, Iran. 107 patients with confirmed COVID-19 pneumonia according to WHO interim guidance were recruited in this study. Extra-pulmonary manifestations of COVID-19 were recorded. SPSS version 26 was used for all the analyses.

Results: The mean (SD) and the median age were 59.3 (17.4) and 62.0 years, respectively and 58 (54.2%) were men. Body temperature of the patients who were equal or less than 60 years was significantly higher than other patients (39.02 vs. 38.08°C, p=0001). The most common extra-pulmonary manifestation was GI symptoms including nausea, vomiting, abdominal pain, diarrhea, hepatocellular Liver Function Test (LFT) abnormality, cholestatic LFT abnormality, and amylase lipase incensement [37 patients (34.6%]. Ophthalmological, cardiac, neurological and dermatological manifestations were shown in 6.5, 6.5, 14.9 and 14.0% of the patients, respectively.

Conclusion: Investigating the clinical and radiological symptoms of COVID-19 showed that SARS-CoV-2 infection may also be associated with extrapulmonary symptoms. Therefore, clinicians and radiologists should be familiar with such symptoms of the disease.