Tutorial on Comorbidity Indices in Medical Research

  • Muhammad Ajmal Dina Center for healthcare Data modeling, Departments of biostatistics and Epidemiology, School of public health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  • Farzan Madadizadeh Center for healthcare Data modeling, Departments of biostatistics and Epidemiology, School of public health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  • Anam Arshed Rahbar Medical and Dental College, Lahore Pakistan
Keywords: CCI (Comorbidity by Charlson Index); ECI (Elixhauser comorbidity index; AML (Acute myeloid leukemia); CDI (Chronic disease index); Indices; Research

Abstract

Background: Comorbidity indices, such as Charlson Comorbidity Index (CCI) and Elixhauser Comorbidity Measure (ECM), are essential tools for assessing the influence of comorbid health conditions on patient outcomes. This study aims to review comorbidity indices by assigning weighted scores to a spectrum of comorbidities; these instruments play a critical role in predicting mortality rates and evaluating healthcare resource utilization.

Methods: In this narrative review study, we reviewed all comorbidity indices and important points were mentioned.

Results: CCIand ECIhave proven to be highly effective tools for predicting mortality and healthcare outcomes across a wide range of patient populations. This review examines four comorbidity indices: CCI, ECI, Acute Myeloid Leukemia (AML), and the Chronic Disease Index (CDI).

Conclusion: Among four types, CCI and ECM were the most applied, and the researcher should know different types of comorbidity indices to use in research

Published
2025-06-01
Section
Articles