Cases of Mediterranean spotted fever in southeast of Iran

Mehrdad  Farrokhnia; Zohreh  Yousefi Ghalejoogh; Mahdi   Rohani; Ahmad  Ghasemi; Saber  Esmaeili; Ehsan  Mostafavi

doi:10.18502/ijm.v12i3.3244

Mehrdad Farrokhnia
Zohreh Yousefi Ghalejoogh
Mahdi Rohani
Ahmad Ghasemi
Saber Esmaeili
Ehsan Mostafavi

DOI: https://doi.org/10.18502/ijm.v12i3.3244

Keywords: Mediterranean spotted fever; Rickettsia conorii; Tache noire; Tick-borne disease

Abstract

In this study the clinical manifestations, laboratory findings, and management of five patients diagnosed with Mediterra- nean spotted fever (MSF) from southeast of Iran are presented. All patients but one had recent tick-bite histories which were noticeable as black eschars (tache noire). Patients’ samples were tested by real-time PCR and serology (IFA). The disease was confirmed by fourfold rising of IgG antibodies against Rickettsia conorii. This is the first report of MSF cases in Iran.