The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern Iran

Authors

  • Zahra Rafat Department of Medical Parasitology and Mycology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
  • Davoud Roostaei Department of Pharmacology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
  • Mohammadreza Mobayen Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran
  • Hamid Salehiniya Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran
  • Parimah Pournasrolah Student Research Committee, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran

DOI:

https://doi.org/10.18502/ijm.v16i6.17262

Keywords:

Candidemia; Burns; Epidemiology; Microbiology; Microbial sensitivity tests

Abstract

Background and Objectives: The study aimed to investigate the epidemiology and clinical therapy of candidemia in burn patients hospitalized in Velayat Hospital, Rasht, Iran.

Materials and Methods: The blood samples of suspected patients were cultured and PCR-sequencing was performed. An-tifungal susceptibility testing was done by the CLSI M27-A4 document.

Results: Four blood samples were identified as positive. Candida parapsilosis complex (3 out of 4, 75%) was the predomi- nant leading cause of candidemia. MIC values showed that all isolates were susceptible to itraconazole, amphotericin B, and 5-flucytosine.

Conclusion: It seems necessary to pay attention to Candida non-albicans species in antifungal therapy.

 

 

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Published

2024-12-14

Issue

Volume (16) issue (6)

Section

Articles