The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern Iran

Zahra  Rafat; Davoud  Roostaei; Mohammadreza  Mobayen; Hamid  Salehiniya; Parimah  Pournasrolah

doi:10.18502/ijm.v16i6.17262

Zahra Rafat Department of Medical Parasitology and Mycology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Davoud Roostaei Department of Pharmacology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Mohammadreza Mobayen Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran
Hamid Salehiniya Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran
Parimah Pournasrolah Student Research Committee, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran

DOI: https://doi.org/10.18502/ijm.v16i6.17262

Keywords: Candidemia; Burns; Epidemiology; Microbiology; Microbial sensitivity tests

Abstract

Background and Objectives: The study aimed to investigate the epidemiology and clinical therapy of candidemia in burn patients hospitalized in Velayat Hospital, Rasht, Iran.

Materials and Methods: The blood samples of suspected patients were cultured and PCR-sequencing was performed. An-tifungal susceptibility testing was done by the CLSI M27-A4 document.

Results: Four blood samples were identified as positive. Candida parapsilosis complex (3 out of 4, 75%) was the predomi- nant leading cause of candidemia. MIC values showed that all isolates were susceptible to itraconazole, amphotericin B, and 5-flucytosine.

Conclusion: It seems necessary to pay attention to Candida non-albicans species in antifungal therapy.