Risk analysis of candidemia and its effect on mortality in COVID 19 and non COVID 19 patients

Gülşah Ece Özmerdiven; Arzu İrvem; Ayça Sultan Şahin

doi:10.18502/ijm.v16i2.15357

Gülşah Ece Özmerdiven Department of Microbiology, Kanuni Sultan Suleyman Research and Training Hospital, Istanbul, Turkey
Arzu İrvem Department of Microbiology, Kanuni Sultan Suleyman Research and Training Hospital, Istanbul, Turkey
Ayça Sultan Şahin Department of Anesthesia and Reanimation, Kanuni Sultan Suleyman Research and Training Hospital, Istanbul, Turkey

DOI: https://doi.org/10.18502/ijm.v16i2.15357

Keywords: Bloodstream infections; Candidemia; COVID 19

Abstract

Background and Objectives: Candidemia is the most common serious fungal infection in critically ill patients in intensive care units (ICU). It series fourth among bloodstream infectious agents. In this study, candidemia risk analysis was examined in COVID 19 and non-COVID 19 patients during the pandemic period.

Materials and Methods: COVID 19 and non-COVID 19 cases who were followed up with candidemia in the ICU of our hospital were retrospectively screened. Demographic data, intubation, central venous catheter (CVC), medications, and to- tal parenteral nutrition (TPN) status were evaluated in terms of risk between the two groups. Isolated Candida species and susceptibilty were evaluated.

Results: When age, gender, medication, intubation, TPN and CVC were evaluated, no difference was seen in terms of risk. Differences were detected in terms of comorbidities. While the most frequently identified Candida species was C. albicans, the most frequently detected species in the COVID19 patient group was C. parapsilosis.

Conclusion: There was no difference in candidemia incidence and risk factors between the two groups. Since candidemias were evaluated in terms of comorbidities, it was determined that Diabetes Mellitus (DM) and chronic obstructive pulmoner disease (COPD) were more common in patients with COVID 19 and less common in coronary artery disease (CAD) and malignancy.