A case of onychomycosis caused by a terbinafine-susceptible Fusarium solani in Vietnam

Thi Minh Chau Ngo; Phuong Anh  Ton Nu; Le Chi Cao; Thi Ngoc  Thuy Ha; Thi Bich Thao Do; Giang Tran Thi

doi:10.18502/ijm.v14i6.11269

Thi Minh Chau Ngo Department of Parasitology, Hue University of Medicine and Pharmacy, Hue University, Hue, Viet Nam
Phuong Anh Ton Nu Department of Parasitology, Hue University of Medicine and Pharmacy, Hue University, Hue, Viet Nam
Le Chi Cao Department of Parasitology, Hue University of Medicine and Pharmacy, Hue University, Hue, Viet Nam
Thi Ngoc Thuy Ha Department of Parasitology, Hue University of Medicine and Pharmacy, Hue University, Hue, Viet Nam
Thi Bich Thao Do Department of Parasitology, Hue University of Medicine and Pharmacy, Hue University, Hue, Viet Nam
Giang Tran Thi Department of Parasitology, Hue University of Medicine and Pharmacy, Hue University, Hue, Viet Nam

DOI: https://doi.org/10.18502/ijm.v14i6.11269

Keywords: Onychomycosis; Fusarium solani; Terbinafine susceptible; Antifungal susceptibility testing; Onychomycosis treatment

Abstract

Fusarium spp. are the common onychomycosis pathogens in non-dermatophyte molds, and are considered resistant to many antifungal agents. We reportedonychomycosis of the fingernail caused by Fusarium solani in Vietnam. The minimum inhib- itory concentration of terbinafine against the tested isolate was1µg/ml, which was the lowest of all antimycotic agents. The patient was successfully treated with a daily dose of 250mg terbinafine for two months, and norecurrence occurred after a one-year follow-up. Antifungal susceptibility testing is recommended in Fusarium onychomycosis.