Combined Treatment of Progressive Encephalitis in an X-linked Agammaglobulinemia Patient
Keywords:
Agammaglobulinemia; Immunomodulators; Primary immunodeficiency diseases; Neuroinflammatory diseases; Therapy
Abstract
Most patients with X-linked agammaglobulinemia are susceptible to infections, while some cases also suffer from inflammatory or autoimmune complications. We describe a patient with progressive encephalitis who improved after the use of immunomodulatory treatment with corticosteroids, fluoxetine, and nitazoxanide. In most of the cases the evolution of the progressive encephalitis is complicated and catastrophic. Based on our experience and the review of the literature, we propose the use of this combined treatment to control this devastating complication.
