Correlation of immature/total granulocyte ratio with return of spontaneous circulation and early mortality in nontraumatic out-of-hospital cardiac arrest

Ersin Kırış; Gülşah Çıkrıkçı Işık; Fatma Nur Karaarslan; Seref Kerem  Çorbacıo˘glu; Emine Emektar; Yunsur Çevik

doi:10.18502/fem.v7i3.13823

Ersin Kırış Department of Emergency Medicine, Ankara Etlik City Hospital, Ankara, Turkey.
Gülşah Çıkrıkçı Işık Department of Emergency Medicine, Ankara Atatürk Sanatoryum Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Fatma Nur Karaarslan Department of Emergency Medicine, Ankara Atatürk Sanatoryum Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Seref Kerem Çorbacıo˘glu Department of Emergency Medicine, Ankara Atatürk Sanatoryum Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Emine Emektar Department of Emergency Medicine, Ankara Atatürk Sanatoryum Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Yunsur Çevik Department of Emergency Medicine, Ankara Atatürk Sanatoryum Training and Research Hospital, University of Health Sciences, Ankara, Turkey.

DOI: https://doi.org/10.18502/fem.v7i3.13823

Keywords: Immature Granulocyte; Out-of-Hospital Cardiac Arrest; Return of Spontaneous Circulation

Abstract

Objective: Aim of this study was to examine immature granulocyte/total granulocyte (IG/TG) ratio for prediction of return of spontaneous circulation (ROSC) and early mortality in post cardiac arrest survivors.

Methods: The study was carried out prospectively between January 2021 and January 2022. Non-traumatic out-of-hospital cardiac arrest (OHCA), over the age of 18 and non-pregnant were included. Patients’ whose IG levels were not studied, with hematological disease and who receiving immunosuppressive therapy were excluded. A palpable pulsation of the main arteries for at least 15 minutes was considered ROSC. Data were compared between the<4 hour and ≥4 hour survival groups and patients with and without ROSC.

Results: Total of 254 OHCA patients were included in the study. ROSC was achieved in 84 (33.1%) of these patients and 170 (66.9%) patients were died. There were 28 patients (33.3%) with survival of <4 hours and 56 patients (66.7%) with survival of ≥4 hours in patients with ROSC. The IG count and IG/TG ratio did not differ significantly between the ROSC groups and between the groups separated by survival time (P>0.05).

Conclusion: We found no significant differences between subgroups defined according to survival duration. Similarly, no differences found between OHCA patients with and without sustained ROSC.