Relationship of the systemic immuno-inflammation index and hematological inflammatory index with mortality and hospitalization in acute pancreatitis: a cross-sectional study

Serdar Özdemir; İbrahim Altunok; Abdullah Algın

doi:10.18502/fem.v7i2.12765

Serdar Özdemir Department of Emergency Medicine, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkey.
İbrahim Altunok Department of Emergency Medicine, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkey.
Abdullah Algın Department of Emergency Medicine, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkey.

DOI: https://doi.org/10.18502/fem.v7i2.12765

Keywords: Blood Platelets; Lymphocytes; Neutrophils; Pancreatitis

Abstract

Objective: This study was conducted to reveal the relationship of the hematological inflammatory index (HII) and systemic immuno-inflammation index (SII) with short-term and prolonged hospitalization in cases of acute pancreatitis.

Methods: This single-center cross-sectional study was conducted in the emergency department (ED) of an educational hospital. The study population contained cases who untaken to the ED with acute pancreatitis between August 15, 2021, and May 15, 2022. Cases discharged from the ED, those referred to another center for hospitalization, and those with absent information were excluded from the study. The patients were grouped according to the length of hospital stay (expected and prolonged) and short-term mortality (survivor and died). We constructed a receiver operating characteristic (ROC) curve for short-term mortality and prolonged hospitalization and obtained the area under the curve (AUC) values for SII and HII.

Results: One hundred seventy-seven patients were included in the study. There was no significant difference between the expected and prolonged hospitalization groups in the terms of SII and HII (P=0.649 and P=0.084, respectively). There was also no significant difference between the survivor and died groups in the terms of these indexes (P=0.070 for HII and P=0.138 for SII). The AUC values for the SII and HII in the prediction of 30-day mortality were 0.616 and 0.642, respectively. The AUC values for the SII and HII in the prediction of prolonged hospitalization were 0.580 and 0.642, respectively.

Conclusion: The outcomes of the present study showed no significant difference among the expected and prolonged hospitalization groups or the survivor and died groups in the terms of SII and HII. We recommend the validation of our results in multicenter studies with larger samples.