https://publish.kne-publishing.com/index.php/fid <p><strong><em>Frontiers in Dentistry (Formerly known as :Journal of Dentistry of Tehran University of Medical Sciences (JDT))</em></strong>&nbsp;is the first Iranian dental journal in English.&nbsp;<strong><em>FD</em></strong>&nbsp;is an Open Access,&nbsp;Peer-Reviewed bimonthly journal published by Dental Research Center (DRC) of Tehran University of Medical Sciences which is a dynamic, rapidly growing research center.</p> <p>The Journal aims to publish novel and high quality relevant information written by peers to researchers and readers involved in all fields of dentistry, oral health sciences and related&nbsp;<span dir="LTR">interdisciplinaries,&nbsp;</span>strives to keep pace with the rapid growth of publications, and move on to the edge of knowledge in this field.</p> <p><strong data-stringify-type="bold">All the manuscripts should be submitted through the Journal Primary Website at <a href="https://fid.tums.ac.ir/index.php/fid/about/submissions">https://fid.tums.ac.ir/index.php/fid/about/submissions</a></strong></p> Tehran University of Medical Sciences en-US Frontiers in Dentistry 2676-296X https://publish.kne-publishing.com/index.php/fid/article/view/22010 <p><strong>Objectives: </strong>This study assessed the effects of erbium, chromium: yttrium, scandium, gallium, and garnet (Er,Cr:YSGG) laser irradiation and eggshell solution on enamel resistance to lemonade-induced erosion.</p> <p><strong>Materials and Methods: </strong>This in vitro study was conducted on 40 surgically extracted mandibular third molars. After initial microhardness measurement, the specimens were assigned to five groups (n=8), including three experimental and two control groups. The experimental group specimens received (I) Er,Cr:YSGG laser irradiation, (II) eggshell solution, and (III) Er,Cr:YSGG laser plus eggshell solution. The positive and negative controls were fluoride and artificial saliva, respectively. Microhardness was reassessed after treatment, erosion, and pH cycling. Data were analyzed by repeated measures ANOVA, Tukey’s test, and paired t-test (alpha=0.05).</p> <p><strong>Results: </strong>After fluoride application, microhardness slightly increased compared to baseline (0.92%); whereas a decrease in microhardness was observed in other groups (-6.71% for laser, -1.78% for laser + eggshell solution, -6.01% for eggshell solution and -10.54% for artificial saliva). Changes in microhardness at different steps were insignificant in the fluoride (P=0.09) and eggshell (P=0.09) groups. A statistically significant descending trend was observed in microhardness of laser (P=0.003), and laser + eggshell (P=0.02) groups but the microhardness change at different steps was not significant in the artificial saliva group (P=0.34).</p> <p><strong>Conclusion:</strong> An increase in microhardness was observed in the fluoride group after remineralization, and its microhardness reduction was not significant after demineralization. Fluoride was more effective than artificial saliva, Er,Cr:YSGG laser, eggshell solution, and eggshell solution plus Er,Cr:YSGG laser in enhancing enamel resistance to lemonade-induced erosion.</p> Fatemeh Dehghani Roza Haghgoo Mohammad Asnaashari Hossein Dehghan Copyright (c) 2026 Frontiers in Dentistry 2026-07-12 2026-07-12 10.18502/fid.v23i20.22010