https://publish.kne-publishing.com/index.php/fid <p><strong><em>Frontiers in Dentistry (Formerly known as :Journal of Dentistry of Tehran University of Medical Sciences (JDT))</em></strong>&nbsp;is the first Iranian dental journal in English.&nbsp;<strong><em>FD</em></strong>&nbsp;is an Open Access,&nbsp;Peer-Reviewed bimonthly journal published by Dental Research Center (DRC) of Tehran University of Medical Sciences which is a dynamic, rapidly growing research center.</p> <p>The Journal aims to publish novel and high quality relevant information written by peers to researchers and readers involved in all fields of dentistry, oral health sciences and related&nbsp;<span dir="LTR">interdisciplinaries,&nbsp;</span>strives to keep pace with the rapid growth of publications, and move on to the edge of knowledge in this field.</p> <p><strong data-stringify-type="bold">All the manuscripts should be submitted through the Journal Primary Website at <a href="https://fid.tums.ac.ir/index.php/fid/about/submissions">https://fid.tums.ac.ir/index.php/fid/about/submissions</a></strong></p> Tehran University of Medical Sciences en-US Frontiers in Dentistry 2676-296X https://publish.kne-publishing.com/index.php/fid/article/view/18868 <p><strong>Objectives: </strong>This study evaluated the effect of bioactive glass (BAG) in different forms on microshear bond strength (µSBS) of composite resin to dentin using a universal adhesive in self-etch (SE) and etch-and-rinse (E&amp;R) modes after different storage times.</p> <p><strong>Materials and Methods: </strong>In this in vitro study, 120 extracted human third molars were sectioned 3mm occlusal to their cementoenamel junction to expose dentin. The teeth were then randomly assigned to three groups (n=40): (I) 20% BAG suspension for dentin pretreatment, (II) 1% BAG-modified adhesive (G2-Bond Universal), and (III) BAG-free control group. Each group was subdivided based on the adhesive application mode (SE or E&amp;R) and storage time (immediate at 24 hours, or delayed at 3 months), with 10 teeth per each subgroup. The µSBS was measured by a universal testing machine. Data were analyzed by three-way and two-way ANOVA, followed by the Tukey's post-hoc test (α=0.05).</p> <p><strong>Results: </strong>Three-way ANOVA showed significant interaction effect of BAG incorporation and storage time on µSBS (P=0.017); while other interactions were not significant (P&gt;0.05). The effects of BAG incorporation (P=0.951) and application mode (P=0.769) were not significant on immediate µSBS (P&gt;0.05). After 3 months, the 1% BAG-modified adhesive showed a significantly higher µSBS than the 20% BAG suspension (P=0.001) and the control group (P&lt;0.001), with no significant effect of application mode (P=0.417).</p> <p><strong>Conclusion:</strong> BAG incorporation did not affect the immediate µSBS of the adhesive but improved its long-term durability, such that the 1% BAG-modified adhesive showed the highest delayed µSBS, regardless of the application mode.</p> Seyed Mostafa Mosavinasab Kamyar Fathpoor Babak Sarrafpoor Mohamad Hossein Fakour Copyright (c) 2025 Frontiers in Dentistry 2025-06-09 2025-06-09 10.18502/fid.v22i24.18868