https://publish.kne-publishing.com/index.php/fid/issue/feedFrontiers in Dentistry2026-01-05T10:38:01+00:00Adminm.davvari@knowledgee.comOpen Journal Systems<p><strong><em>Frontiers in Dentistry (Formerly known as :Journal of Dentistry of Tehran University of Medical Sciences (JDT))</em></strong> is the first Iranian dental journal in English. <strong><em>FD</em></strong> is an Open Access, Peer-Reviewed bimonthly journal published by Dental Research Center (DRC) of Tehran University of Medical Sciences which is a dynamic, rapidly growing research center.</p> <p>The Journal aims to publish novel and high quality relevant information written by peers to researchers and readers involved in all fields of dentistry, oral health sciences and related <span dir="LTR">interdisciplinaries, </span>strives to keep pace with the rapid growth of publications, and move on to the edge of knowledge in this field.</p> <p><strong data-stringify-type="bold">All the manuscripts should be submitted through the Journal Primary Website at <a href="https://fid.tums.ac.ir/index.php/fid/about/submissions">https://fid.tums.ac.ir/index.php/fid/about/submissions</a></strong></p>https://publish.kne-publishing.com/index.php/fid/article/view/20714Occlusion of Dentinal Tubules by Nanohydroxyapatite and Zinc Carbonate Hydroxyapatite-Based Toothpastes as Desensitizing Agents: An in Vitro Study 2026-01-05T10:38:01+00:00Shubhankar Mehrotranone@none.comRupali Agnihotrinone@none.com<p><strong>Objectives: </strong>Dentin hypersensitivity (DH), characterized by a short, sharp, and intense pain response to a stimulus, is the most commonly encountered patient complaint. Various in-office and at-home methods including the recently introduced nano-hydroxyapatite (n-HA) and zinc carbonate-hydroxyapatite (Zn-CHA)-based products reduce the DH discomfort. This study compared the effectiveness of commercially available n-HA and Zn-CHA toothpastes for occlusion of dentinal tubules for management of DH.</p> <p><strong>Materials and Methods: </strong>In this in vitro study, 40 tooth samples were randomly assigned to 4 groups (n=10): negative control): brushing without toothpaste,Aclaim n-HA toothpaste,Biorepair Zn-CHA toothpaste, andShyNM calcium sodium phosphosilicate (CSPS) toothpaste. After demineralization with 17% ethylenediaminetetraacetic acid, the mounted specimens were brushed with an electric pressure-sensitive toothbrush and the respective toothpaste. Occlusion of dentinal tubules was subsequently evaluated under a scanning electron microscope (SEM). Elemental composition of the occluding plug was analyzed by energy-dispersive X-ray spectroscopy (EDX).</p> <p><strong>Results: </strong>The test n-HA and Zn-CHAand the positive control (CSPS) groups revealed significantly higher tubular occlusion compared to the negative control group (p= 0.001). The highest tubular occlusion was achieved in n-HA and Zn-CHA groups (80%); while negative control showed no occlusion (0%). Elemental analysis of dentinal plug showed significant differences in carbon, oxygen, calcium, and phosphorus levels among the groups (p<0.05).</p> <p><strong>Conclusion:</strong> The tubular occlusion capacity of Zn-CHA and n-HA were similar to CSPS-based toothpaste, and CHA in Zn-CHA enabled the formation of stable dentinal plugs.</p>2026-01-05T08:13:30+00:00Copyright (c) 2026 Frontiers in Dentistry