Comparison of Modified Open Prostatectomy and Classic TURP in Patients with Benign Prostatic Hyperplasia: A Clinical Trial

Hormoz Karami; Alireza Ayatolahi; Mohsen Ahrari; Moein Bighamian; Farzan Safi Dahaj; Amirali Eslami

doi:10.18502/ssu.v30i1.9103

Hormoz Karami Department of Urology, School of Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Alireza Ayatolahi School of Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Mohsen Ahrari School of Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Moein Bighamian School of Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Farzan Safi Dahaj School of Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Amirali Eslami School of Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.

DOI: https://doi.org/10.18502/ssu.v30i1.9103

Keywords: Benign Prostatic Hyperplasia, Open prostatectomy, Transurethral resection of the prostate.

Abstract

Introduction: The aim of this study was to compare the results of recovery of patients with benign prostatic hyperplasia through two surgical methods, including TURP (Transurethral resection of prostate) and modified open prostatectomy (OP) was performed.

Methods: In this clinical trial study, 100 patients with benign prostatic hyperplasia who were referred to the Urology Clinic of Shahid Rahnemon Hospital from 1996 to 1997 were admitted to the study on the inclusion and exclusion criteria and were randomly assigned to one of the surgical groups using the modified OP or TURP approach. The results of the study in both groups were analyzed through SPSS 16 software. Due to the normal distribution of data, T-test and Chi-Square statistical tests were applied to analyze the data.

Results: The mean age of the patients undergoing modified OP surgery and the TURP patients was 70.36 ± 8.35 and 69.39 ± 8.44 years, respectively. The maximum urinary flow (Qmax) was significantly higher in the modified OP group than in the TURP group (P <0.001). In addition, the mean duration of operation in the modified OP group was significantly lower than the TURP group (P = 0.001). The increase in obstructive and excitatory symptoms in the TURP group was statistically significant 6 months after surgery (P = 0.009 and P = 0.011, respectively).

Conclusion: While TURP is the standard therapy for patients with BPH‎, the findings of this study indicate that modified OP is a safer and more reliable procedure with fewer postoperative complications. It is recommended that modified OP be considered as a treatment for the patients with BPH.